Lactobacillus rhamnosus MAK79L08R and Reduced Gastrointestinal Symptoms

• No Evidence of Harms of Probiotic Lactobacillus rhamnosus GG ATCC 53103 in Healthy Elderly—A Phase I Open Label Study to Assess Safety, Tolerability and Cytokine Responses

  • 2014-12-01
  • Clinical Trial · n = 15
  • PLoS ONE 9(12)
  • • P. Hibberd
    • L. Kleimola
    • Anne‐Maria Fiorino
    • Christine Botelho
    • Miriam Haverkamp
    • Irina Andreyeva
    • D. Poutsiaka
    • C. Fraser
    • G. Solano-Aguilar
    • D. Snydman

  • PubMed: 25438151
  • DOI: 10.1371/journal.pone.0113456

  10 Insights on

  • Reduced Gastrointestinal Symptoms

  • High evidence
  • Rigorous Journal
  • Elderly

  The most common adverse events were gastrointestinal (bloating, gas, and nausea), 27 rated as mild and 3 rated as moderate.

  Effect

  Neutral

  Effect size

  Small