Lactobacillus rhamnosus PXN 54 and No Significant Improvement in ADHD Symptoms

• Therapeutic efficacy of probiotics for symptoms of attention-deficit hyperactivity disorder in children and adolescents: meta-analysis.

  • 2024-01
  • Review · n = 379
  • BJPsych open 10(1)
  • • Shun-Chin Liang
    • Cheuk-Kwan Sun
    • Chih-Hua Chang
    • Yu-Shian Cheng
    • Ruu-Fen Tzang
    • Hsien-Jane Chiu
    • Ming Yu Wang
    • Ying-Chih Cheng
    • Kuo-Chuan Hung

  • PubMed: 38268113
  • DOI: 10.1192/bjo.2023.645

  2 Insights on

  • No Significant Improvement in ADHD Symptoms

  • High evidence

  Meta-analysis of seven trials involving 379 participants ... showed no significant improvement in total symptoms of ADHD ... symptoms of inattention ... or hyperactivity/impulsivity ... between the probiotic and placebo groups.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No