Lactobacillus rhamnosus R0011 and Increased Anti-Inflammatory Cytokine IL-10

• Probiotics (Lactobacillus rhamnosus R0011 and acidophilus R0052) reduce the expression of toll-like receptor 4 in mice with alcoholic liver disease.

  • 2015-02-18
  • PloS one 10(2)
  • • Meegun Hong
    • Seung Woo Kim
    • Sang Hak Han
    • Dong Joon Kim
    • Ki Tae Suk
    • Yeon Soo Kim
    • Myong Jo Kim
    • Moon Young Kim
    • Soon Koo Baik
    • Young Lim Ham

  • PubMed: 25692549
  • DOI: 10.1371/journal.pone.0117451

  2 Insights on

  • Increased Anti-Inflammatory Cytokine IL-10

  • Low evidence
  • Animal Study

  In the H group, IL-10 was significantly increased by probiotics and KRG, compared with alcohol (25.3±15.6 and 20.4±6.2 vs. 7.6±5.6 pg/mL)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes