Suppression of Intestinal Epithelial Cell Chemokine Production by Lactobacillus rhamnosus R0011 and Lactobacillus helveticus R0389 Is Mediated by Secreted Bioactive Molecules.
- 2018-11-14
- Frontiers in immunology 9
- Michael P Jeffrey
- Janice L Strap
- Holly Jones Taggart
- Julia M Green-Johnson
- PubMed: 30524427
- DOI: 10.3389/fimmu.2018.02639
- Low evidence
Lr-CFS and Lh-CFS significantly down-regulated IL-8 production from HT-29 IECs challenged with varied PRR ligands. ... Further analysis of the Lr-CFS revealed down-regulation of IL-8 production induced by the pro-inflammatory cytokines IL-1β and TNFα
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes