Lactobacillus rhamnosus R0011 and Reduced Pro-Inflammatory Cytokines

• Probiotics (Lactobacillus rhamnosus R0011 and acidophilus R0052) reduce the expression of toll-like receptor 4 in mice with alcoholic liver disease.

  • 2015-02-18
  • PloS one 10(2)
  • • Meegun Hong
    • Seung Woo Kim
    • Sang Hak Han
    • Dong Joon Kim
    • Ki Tae Suk
    • Yeon Soo Kim
    • Myong Jo Kim
    • Moon Young Kim
    • Soon Koo Baik
    • Young Lim Ham

  • PubMed: 25692549
  • DOI: 10.1371/journal.pone.0117451

  2 Insights on

  • Reduced Pro-Inflammatory Cytokines

  • Low evidence
  • Animal Study

  probiotics, KRG, and urushiol significantly reduced levels of TNF-α ... and IL-1β ... which were increased by alcohol.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes