Milk containing probiotic Lactobacillus rhamnosus GG and respiratory illness in children: a randomized, double-blind, placebo-controlled trial
- 2012-06-13
- RCT · n = 523
- European Journal of Clinical Nutrition 66(9)
- M. Kumpu
- R. Kekkonen
- Hannu J. Kautiainen
- S. Järvenpää
- A. Kristo
- P. Huovinen
- A. Pitkäranta
- R. Korpela
- K. Hatakka
- PubMed: 22692023
- DOI: 10.1038/ejcn.2012.62
- High evidence
- Large Human Trial
- Highly Cited
- Rigorous Journal
- Children
Number of days with at least one respiratory symptom in all subjects was 5.03/month (95% confidence interval (CI): 4.92-5.15) in the GG group and 5.17/month (95% CI: 5.05-5.29) in the placebo group incidence rate ratio (IRR) 0.97; 95% CI: 0.94-1.00; P=0.098).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No