Lactobacillus rhamnosus L34 attenuates chronic kidney disease progression in 5/6 nephrectomy mouse model through the excretion of anti-inflammatory molecules.
- 2022-02-09
- Nephrology Dialysis Transplantation 37(8)
- S. Tungsanga
- P. Katavetin
- Wimonrat Panpetch
- Kanyarat Udompornpitak
- Wilasinee Saisorn
- K. Praditpornsilpa
- S. Eiam‐Ong
- K. Tungsanga
- S. Tumwasorn
- A. Leelahavanichkul
- PubMed: 35138387
- DOI: 10.1093/ndt/gfac032
- Low evidence
L34-treated mice showed significantly fewer renal injuries, with lower GDUT including trimethylamine-N-oxide (TMAO) (P = 0.02) and indoxyl sulfate (P < 0.01).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes