Activity in an air-liquid interface lung infection model, feasibility of inhaled delivery, and stability of cell-free supernatants from Lacticaseibacillus rhamnosus against Pseudomonas aeruginosa pulmonary infections.
- 2025-08-05
- Frontiers in microbiology 16
- Anna Maria Piras
- Marta Bianchi
- Nicolò Della Bona
- Brunella Grassiri
- Esingül Kaya
- Andrea Bertacca
- Chiara Migone
- Giuseppantonio Maisetta
- Semih Esin
- Giovanna Batoni
- PubMed: 40838010
- DOI: 10.3389/fmicb.2025.1630017
- Low evidence
Aerodynamic testing with the TSI and an Aerogen® mesh nebulizer showed that 76% of the nebulized product was deposited in the second stage, indicating effective deep lung delivery.
- Effect
- Beneficial
- Effect size
- Moderate