Intranasally inoculated bacterium-like particles displaying porcine epidemic diarrhea virus S1 protein induced intestinal mucosal immune response in mice.
- 2023-09-18
- Frontiers in immunology 14
- Kai Su
- Yawen Wang
- Chen Yuan
- Yanan Zhang
- Yanrui Li
- Tanqing Li
- Qinye Song
- PubMed: 37790942
- DOI: 10.3389/fimmu.2023.1269409
- Low evidence
- Animal Study
The specific IgG titer in serum of intramuscularly immunized mice with S1-BLPs was significantly higher than that of the intranasally administered.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes