Lactobacillus rhamnosus and Modulated Gut Microbiome Composition

• Probiotic Lactobacillus rhamnosus mitigates PBC-like features in Mcpip1-deficient mice via modulation of gut-liver crosstalk.

  • 2026-06
  • Biochimica et biophysica acta. Molecular basis of disease 1872(5)
  • • Katarzyna Trzos
    • Tomasz Hutsch
    • Anastasiia Koval
    • Danuta Śmierciak
    • Gabriela Machaj
    • Leidy-Alejandra G Molano
    • Jacqueline Rehner
    • Md Mobashir Rahman
    • Maximilian Olaf Förster
    • Marcin Bednarek
    • Bahtiyar Yilmaz
    • Magdalena Pilarczyk-Zurek
    • Szymon Surma
    • Joanna Koziel
    • Marcin Krawczyk
    • Andreas Keller
    • Sören L Becker
    • Guillem Ylla
    • Jolanta Jura
    • Jerzy Kotlinowski

  • PubMed: 41846103
  • DOI: 10.1016/j.bbadis.2026.168216

  1 Insight on

  • Modulated Gut Microbiome Composition

  • Low evidence
  • Animal Study

  probiotic treatment modulated the microbiome by increasing the Firmicutes/Bacteroidetes ratio and enriching butyrate-producing Lachnospiraceae.

  Effect

  Beneficial

  Effect size

  Small