Efficacy of Probiotic Strains Lactobacillus sakei Probio65 and Lactobacillus plantarum Probio-093 in Management of Obesity: An In Vitro and In Vivo Analysis.
- 2024-05-24
- Pharmaceuticals (Basel, Switzerland) 17(6)
- Aneela Gulnaz
- Lee-Ching Lew
- Yong-Ha Park
- Jamal S M Sabir
- Raed Albiheyri
- Irfan A Rather
- Yan-Yan Hor
- PubMed: 38931347
- DOI: 10.3390/ph17060676
- Low evidence
both strains modulated adipokine profiles by downregulating proinflammatory markers such as PAI-1, leptin, TNF-α, STAMP2, F4/80, resistin, and MCP-1, and upregulating the insulin-sensitive transporter GLUT4 and the anti-inflammatory adiponectin (p < 0.05).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes