Lactobacillus sakei proBio65 and Reduced Atopic Dermatitis Severity

• Oral Administration of Live and Dead Cells of Lactobacillus sakei proBio65 Alleviated Atopic Dermatitis in Children and Adolescents: a Randomized, Double-Blind, and Placebo-Controlled Study

  • 2020-09-18
  • RCT · n = 90
  • Probiotics and Antimicrobial Proteins 13(2)
  • • I. Rather
    • Byung-Chun Kim
    • L. Lew
    • S. Cha
    • Jong Hwan Lee
    • Gyeong-Jun Nam
    • R. Majumder
    • Jeongheui Lim
    • S. Lim
    • Y. Seo
    • Yong-Ha Park

  • PubMed: 32949011
  • DOI: 10.1007/s12602-020-09654-7

  4 Insights on

  • Reduced Atopic Dermatitis Severity

  • High evidence

  The SCORAD total score decreased in the live cells (p = 0.0015) and dead cell group (p = 0.0017) from the baseline after 12 weeks, whereas there were no significant changes in the placebo group when compared with baseline.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes