Lactobacillus sakei proBio65 and Reduced Gastrointestinal Symptoms

• Novel Application of Oral Postbiotics for Skin Condition in Healthy Middle-Aged Women: A Randomized, Double-Blind, and Placebo-Controlled Study.

  • 2025-12
  • RCT · n = 60
  • Journal of cosmetic dermatology 24(12)
  • • Jinko Sawashita
    • Shinichi Honda
    • Yuji Tominaga
    • Namiko Tomatsu
    • Jordi Espadaler-Mazo
    • Takahiro Ueda

  • PubMed: 41414786
  • DOI: 10.1111/jocd.70617

  7 Insights on

  • Reduced Gastrointestinal Symptoms

  • High evidence

  No exacerbation of gastrointestinal symptoms was seen with postbiotic supplementation, and the frequency of adverse events was similar between the postbiotic and placebo groups.

  Effect

  Neutral

  Effect size

  Small