Lactobacillus sakei proBio65 and Reduced SARS-CoV-2 Replication

• The Inhibition of SARS-CoV-2 and the Modulation of Inflammatory Responses by the Extract of Lactobacillus sakei Probio65.

  • 2022-12-09
  • Vaccines 10(12)
  • • Irfan A Rather
    • Lee-Ching Lew
    • Majid Rasool Kamli
    • Khalid Rehman Hakeem
    • Jamal S M Sabir
    • Yong-Ha Park
    • Yan-Yan Hor

  • PubMed: 36560517
  • DOI: 10.3390/vaccines10122106

  3 Insights on

  • Reduced SARS-CoV-2 Replication

  • Low evidence

  viral load quantification by RT-PCR showed that the P65-CFS inhibited SARS-CoV-2 replication in human embryonic kidney (HEK) 293 cells in a dose-dependent manner, with 150 mg/mL being the most effective concentration (60.16% replication inhibition)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes