Probiotic, Prebiotic, and Synbiotic Supplementation for the Prevention and Treatment of Acute Otitis Media: A Systematic Review and Meta-Analysis.
- 2025-04-30
- Review · n = 4,034
- Children (Basel, Switzerland) 12(5)
- Freiser Eceomo Cruz Mosquera
- Mayerli de la Rosa Caldas
- Anisbed Naranjo Rojas
- Claudia Lorena Perlaza
- Yamil Liscano
- PubMed: 40426770
- DOI: 10.3390/children12050591
- High evidence
the intervention was associated with a reduced probability of developing AOM (RR: 0.80; 95% CI: 0.66 to 0.96; p = 0.02)
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes