Lactobacillus delbrueckii CRL 581 Differentially Modulates TLR3-Triggered Antiviral Innate Immune Response in Intestinal Epithelial Cells and Macrophages.
- 2021-11-27
- Microorganisms 9(12)
- Mariano Elean
- Leonardo Albarracin
- Kohtaro Fukuyama
- Binghui Zhou
- Mikado Tomokiyo
- Shugo Kitahara
- Shota Araki
- Yoshihito Suda
- Lucila Saavedra
- Julio Villena
- Elvira M Hebert
- Haruki Kitazawa
- PubMed: 34946051
- DOI: 10.3390/microorganisms9122449
- Low evidence
The CRL 581 strain also augmented the expression of antiviral factors (IFN-α, IFN-β, Mx1, OAS1, and OAS2) and reduced inflammatory cytokines in PIE cells triggered by TLR3 stimulation.
- Effect
- Beneficial
- Effect size
- Moderate