Lactobacillus salivarius LS-33 and Increased Antioxidant Capacity

• Gut microbiome-derived indole-3-carboxaldehyde promotes intestinal development via AHR-NRF2 signaling in the early-life of chicks.

  • 2025-12-16
  • Clinical Trial
  • Microbiome 14(1)
  • • Yu-Xuan Huang
    • Zhang-Chao Deng
    • Ke-Xin Cao
    • Jia-Cheng Yang
    • Meng Liu
    • Ling Zhao
    • Jin-Shui Zheng
    • Lv-Hui Sun

  • PubMed: 41402846
  • DOI: 10.1186/s40168-025-02289-2

  2 Insights on

  • Increased Antioxidant Capacity

  • Low evidence
  • Rigorous Journal
  • Animal Study

  both bacteria (LG and LS) and metabolites (IAld and ICA) promoted epithelial barrier function and enhanced antioxidant capacity during early life in chicks

  Effect

  Beneficial

  Effect size

  Moderate