Lactobacillus salivarius SD-5208 and Increased Incidence of Dental Caries

• Cariogenicity of the Probiotic Bacterium Lactobacillus salivarius in Rats

  • 2005-11-22
  • Clinical Trial · n = 6
  • Caries Research 39(6)
  • • M. Matsumoto
    • M. Tsuji
    • H. Sasaki
    • K. Fujita
    • R. Nomura
    • K. Nakano
    • S. Shintani
    • T. Ooshima

  • PubMed: 16251792
  • DOI: 10.1159/000088183

  4 Insights on

  • Increased Incidence of Dental Caries

  • Low evidence
  • Animal Study

  L. salivarius LS1952R became established in the oral cavity of rats and induced significant level of dental caries even when infected for only 5 days from 18 to 22 days of age.

  Effect

  Harmful

  Effect size

  Large

  Significant

  Yes