Probiotic effects of orally administered Lactobacillus salivarius WB21-containing tablets on periodontopathic bacteria: a double-blinded, placebo-controlled, randomized clinical trial.
- 2009-05-18
- RCT · n = 66
- Journal of Clinical Periodontology 36(6)
- G. Mayanagi
- Moto Kimura
- S. Nakaya
- H. Hirata
- M. Sakamoto
- Y. Benno
- H. Shimauchi
- PubMed: 19453574
- DOI: 10.1111/j.1600-051X.2009.01392.x
- High evidence
- Highly Cited
- Clinical
The numerical sum of five selected periodontopathic bacteria in the test group was decreased significantly in subgingival plaque at 4W (odds ratio (OR)=3.13, 95% confidence intervals (CI)=1.28-7.65, p=0.012).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes