Lactobacillus salivarius UALs07 and Improved Tolerance to Bile Salts

• Integrated transcriptomic and proteomic analysis of the bile stress response in probiotic Lactobacillus salivarius LI01.

  • 2017-01
  • Journal of Proteomics 150
  • • L. Lv
    • Ren Yan
    • Hai-Yan Shi
    • D. Shi
    • D. Fang
    • Huiyong Jiang
    • Wen-rui Wu
    • F. Guo
    • Xia-wei Jiang
    • Silan Gu
    • Yun-bo Chen
    • Jian Yao
    • Lanjuan Li

  • PubMed: 27585996
  • DOI: 10.1016/j.jprot.2016.08.021

  3 Insights on

  • Improved Tolerance to Bile Salts

  • Low evidence

  Tolerance to bile stress is crucial to allow lactobacilli to survive in the gastrointestinal tract and exert their benefits. In this work, we used a Digital Gene Expression transcriptomic and iTRAQ LC-MS/MS proteomic approach to examine the characteristics of LI01 in response to bile stress.

  Effect

  Beneficial

  Effect size

  Moderate