Lactobacillus salivarius UALs07 and Reduced Immunosuppression in Pharyngitis

• Human-origin Lactobacillus salivarius AR809 protects against immunosuppression in S. aureus-induced pharyngitis via Akt-mediated NF-κB and autophagy signaling pathways.

  • 2020-10-07
  • Clinical Trial
  • Food & Function 11(1)
  • • G. Jia
    • Xiaofeng Liu
    • N. Che
    • Yongjun Xia
    • Guangqiang Wang
    • Z. Xiong
    • Hui Zhang
    • Lian-zhong Ai

  • PubMed: 31957758
  • DOI: 10.1039/c9fo02476j

  8 Insights on

  • Reduced Immunosuppression in Pharyngitis

  • Low evidence
  • Animal Study

  Lactobacillus salivarius AR809 is a newly discovered probiotic strain from a healthy human pharynx and has potential ability to adhere to the pharyngeal epithelium and inhibit Staphylococcus aureus (S. aureus)-induced inflammatory response. Pharyngeal spray administration of AR809 exhibited protective effects in a S. aureus-induced mouse model of pharyngitis.

  Effect

  Beneficial

  Effect size

  Large