Lactobacillus salivarius UCC118 and Enhanced Innate Immune Response

• Lactobacillus salivarius HHuMin-U Activates Innate Immune Defense against Norovirus Infection through TBK1-IRF3 and NF-κB Signaling Pathways.

  • 2022-01
  • Research (Washington, D.C.) 2022
  • • Da Hyun Kim
    • Minju Jeong
    • Jae Hwan Kim
    • Joe Eun Son
    • John J Y Lee
    • Sang-Jun Park
    • Juyeon Lee
    • Minwoo Kim
    • Jong-Won Oh
    • Myeong Soo Park
    • Sanguine Byun

  • PubMed: 39290965
  • DOI: 10.34133/research.0007

  5 Insights on

  • Enhanced Innate Immune Response

  • Low evidence

  HHuMin-U treatment dose-dependently induced type I interferons (IFN-α and IFN-β) and tumor necrosis factor-α production in mouse and human macrophages, promoting antiviral innate responses against norovirus infection.

  Effect

  Beneficial

  Effect size

  Moderate