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Lactobacillus salivarius UCC118 and Improved Glucose Metabolism

Research synthesisModerate evidenceModerate effect4 studies · 4 beneficial · 0 neutral · 0 harmful

Across 4 studies (including 3 meta-analyses), all reported beneficial moderate-sized effects of Lactobacillus salivarius UCC118 on glucose metabolism, particularly in pregnant women. The evidence shows improvements in fasting blood glucose, insulin levels, and HOMA-IR, with the strongest effects observed in women with gestational diabetes mellitus (GDM). No specific dose range or form was consistently reported across studies.

  • Studied populations: pregnant women, particularly those with gestational diabetes mellitus (GDM) or overweight/obese

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Additionally, all studies focused on pregnant women, so benefits for other populations are unknown. No specific dose or form was consistently reported, limiting practical recommendations.

Generated Jul 11, 2026
4 of 4 papers
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