Lactobacillus salivarius UCC118 and No Human Health Outcome Reported

Research synthesisVery low evidenceSmall effect7 studies · 0 beneficial · 7 neutral · 0 harmful

Across 7 studies, all reported neutral and small-sized effects for Lactobacillus salivarius UCC118, with no beneficial or harmful outcomes observed. No studies reported a specific dose, form, or human health outcome directly linked to consumption of this strain. The evidence base is very small and entirely composed of review articles and genomic analyses that do not involve human supplementation trials.

Caveats: Evidence base is small (only 7 studies) — conclusions should be considered preliminary. None of the studies reported any direct human health outcomes for consuming Lactobacillus salivarius UCC118; most were narrative reviews or unrelated metagenomic analyses, so no effect direction can be robustly inferred.

Generated Jun 11, 2026

7 of 7 papers

Effects of Athletic Nutritional Supplements on the Human Gut Microbiota: A Narrative Review.
- 2025-09-26
- Review
- Nutrients 17(19)
- - Themistoklis Katsimichas
  - Anastasia Xintarakou
  - Charalambos Vlachopoulos
  - Costas Tsioufis
  - George Lazaros
- PubMed: 41097148
- DOI: 10.3390/nu17193071
1 Insight on
- No Human Health Outcome Reported
- Moderate evidence
- Rigorous Journal
The provided abstract is a narrative review of athletic nutritional supplements and does not mention any study results or health outcomes specifically for consuming Lactobacillus salivarius UCC118.
Effect
Neutral
Effect size
Small
Metagenomic analysis of soybean endosphere microbiome to reveal signatures of microbes for health and disease.
- 2023-12
- n = 240
- Journal, genetic engineering & biotechnology 21(1)
- - Usha Chouhan
  - Umesh Gamad
  - Jyoti Kant Choudhari
- PubMed: 37584775
- DOI: 10.1186/s43141-023-00535-4
1 Insight on
- No Human Health Outcome Reported
- Moderate evidence
This abstract describes a metagenomic analysis of the soybean endosphere microbiome and does not report any study of consuming Lactobacillus salivarius UCC118 or related health outcomes.
Effect
Neutral
Effect size
Small
Bacteriocins as a new generation of antimicrobials: toxicity aspects and regulations.
- 2020-09-02
- Review
- FEMS microbiology reviews 45(1)
- - Samira Soltani
  - Riadh Hammami
  - Paul D Cotter
  - Sylvie Rebuffat
  - Laila Ben Said
  - Hélène Gaudreau
  - François Bédard
  - Eric Biron
  - Djamel Drider
  - Ismail Fliss
- PubMed: 32876664
- DOI: 10.1093/femsre/fuaa039
3 Insights on
- No Human Health Outcome Reported
- Moderate evidence
- Highly Cited
The provided abstract is a general review of bacteriocins, toxicity, and regulations and does not describe any specific study or observed health outcomes from consuming Lactobacillus salivarius UCC118.
Effect
Neutral
Effect size
Small
A Review of Modulation of Gut Microbiota to Mitigate Gestational Diabetes: Implications for Maternal and Child Health.
- 2025-08-22
- Review
- Medical science monitor : international medical journal of experimental and clinical research 31
- - Olimpia Mora-Janiszewska
  - Kinga Bialic
  - Anna Faryniak
  - Dorota Darmochwał-Kolarz
- PubMed: 40842120
- DOI: 10.12659/msm.948897
3 Insights on
- No Human Health Outcome Reported
- Low evidence
The provided text is a review article title and summary about gut microbiota modulation in gestational diabetes mellitus, but it does not mention any study results or health outcomes specifically for consuming Lactobacillus salivarius UCC118.
Effect
Neutral
Effect size
Small
Gut Microbiota and Critical Metabolites: Potential Target in Preventing Gestational Diabetes Mellitus?
- 2023-06-30
- Review
- Microorganisms 11(7)
- - Runan Hu
  - Zhuo Liu
  - Yuli Geng
  - Yanjing Huang
  - Fan Li
  - Haoxu Dong
  - Wenwen Ma
  - Kunkun Song
  - Mingmin Zhang
  - Yufan Song
- PubMed: 37512897
- DOI: 10.3390/microorganisms11071725
1 Insight on
- No Human Health Outcome Reported
- Low evidence
The provided abstract discusses gut microbiota and gestational diabetes mellitus in general, but does not mention any study of Lactobacillus salivarius UCC118 or any observed health outcomes from consuming it.
Effect
Neutral
Effect size
Small
d-Amino Acids and Lactic Acid Bacteria.
- 2019-12-12
- Review
- Microorganisms 7(12)
- - Jyumpei Kobayashi
- PubMed: 31842512
- DOI: 10.3390/microorganisms7120690
2 Insights on
- No Human Health Outcome Reported
- Low evidence
This review summarizes and introduces the importance of various d-amino acids in this regard.
Effect
Neutral
Effect size
Small
Complete Genome Sequences of Six Lactobacilli Isolated from American Quarter Horses.
- 2020-11-19
- Microbiology resource announcements 9(47)
- - Rachael I Meinders
  - Mary Mendoza
  - Allison N Dickey
  - Elizabeth H Scholl
  - Hosni M Hassan
- PubMed: 33214299
- DOI: 10.1128/mra.00997-20
2 Insights on
- No Human Health Outcome Reported
- Low evidence
We report the complete circular genome sequences of six Lactobacillus strains and their plasmids, if any, from the fecal material of quarter horses at different ages.
Effect
Neutral
Effect size
Small

Lactobacillus salivarius UCC118 and No Human Health Outcome Reported

Effects of Athletic Nutritional Supplements on the Human Gut Microbiota: A Narrative Review.

Metagenomic analysis of soybean endosphere microbiome to reveal signatures of microbes for health and disease.

Bacteriocins as a new generation of antimicrobials: toxicity aspects and regulations.

A Review of Modulation of Gut Microbiota to Mitigate Gestational Diabetes: Implications for Maternal and Child Health.

Gut Microbiota and Critical Metabolites: Potential Target in Preventing Gestational Diabetes Mellitus?

d-Amino Acids and Lactic Acid Bacteria.

Complete Genome Sequences of Six Lactobacilli Isolated from American Quarter Horses.