Probiotics combined with prebiotics alleviated seasonal allergic rhinitis by altering the composition and metabolic function of intestinal microbiota: a prospective, randomized, double-blind, placebo-controlled clinical trial.
- 2024-11-01
- RCT · n = 106
- Frontiers in immunology 15
- Yangfan Hou
- Dan Wang
- Shuru Zhou
- Caifang Huo
- Haijuan Chen
- Fangxia Li
- Minjuan Ding
- Hongxin Li
- Hongyan Zhao
- Jin He
- Hongju Da
- Yu Ma
- Zhihui Qiang
- Xiushan Chen
- Cairong Bai
- Jing Cui
- Na Gao
- Yun Liu
- PubMed: 39555052
- DOI: 10.3389/fimmu.2024.1439830
- High evidence
- Large Human Trial
the INF-γ level was significantly increased (P = 0.01), whereas that of IL-17 (P = 0.005) was significantly decreased in the test group
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes