Lactococcus lactis L1A-23 and Reduced Nasal Inflammation

• Nasal administration of a probiotic assemblage in allergic rhinitis: A randomised placebo-controlled crossover trial.

  • 2022-03-19
  • RCT · n = 24
  • Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 52(6)
  • • Anders Mårtensson
    • Franziska U Nordström
    • Charlotte Cervin-Hoberg
    • Malin Lindstedt
    • Christina Sakellariou
    • Anders Cervin
    • Lennart Greiff

  • PubMed: 35075723
  • DOI: 10.1111/cea.14098

  2 Insights on

  • Reduced Nasal Inflammation

  • High evidence

  no change in nasal lavage fluid levels of cytokines/mediators was observed cf. placebo except for IL-17/IL-17A (a minor increase in the PA run).

  Effect

  Neutral

  Effect size

  Small