Lactococcus lactis LI-23 and Reduced Trichinella Spiralis Infection Burden

• Protective effect of Lactococcus lactis NZ9000 secreting Bcl2 against Trichinella spiralis infection in mice.

  • 2026-01-05
  • BMC veterinary research 22(1)
  • • Ruibiao Wang
    • Suxian Liu
    • Hongyan Zhang
    • Doudou Feng
    • Yukai Lin
    • Siyang Li
    • Jiyuan Shen
    • Bo Wen
    • Huarun Sun
    • Minghui Li
    • Qiangqiang Wang
    • Lan Wei
    • Yuanfang Ma
    • Yixin Lu
    • Lei Wang

  • PubMed: 41491176
  • DOI: 10.1186/s12917-025-05238-1

  3 Insights on

  • Reduced Trichinella Spiralis Infection Burden

  • Low evidence
  • Animal Study

  In low-dose infections (150 larvae/mouse), oral administration of NZ-Bcl2 significantly reduced muscle larval burden, mitigated intestinal damage, and alleviated mesenteric lymph node enlargement.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes