Lactococcus lactis LL-23 and Increased Regulatory T Cell Response

• An oral M-cell targeted Lactococcus lactis vaccine against Echinococcus multilocularis infection.

  • 2025-10-28
  • Frontiers in immunology 16
  • • Yang Xiao
    • Zhao-Hui Luo
    • Shun-Juan Wang
    • Yao Dai
    • Jia-Yu Chen
    • Jia-Yong Cui
    • Run-Le Li
    • Feng Tang

  • PubMed: 41229421
  • DOI: 10.3389/fimmu.2025.1683003

  4 Insights on

  • Increased Regulatory T Cell Response

  • Low evidence
  • Animal Study

  LL-plSAM-GILE stimulated the production of CD4+ and CD8+ T cells.

  Effect

  Beneficial

  Effect size

  Moderate