Oral delivery of engineered Lactococcus lactis microcapsules expressing antioxidant enzymes for inflammatory bowel disease: Mechanisms of intestinal barrier repair and microbiota modulation.
- 2026-04
- Materials today. Bio 37
- Yue Meng
- Chao Miao
- Jiaxin Guo
- Wei Zhang
- Ling Guo
- Yu Zhang
- Yujun Jiang
- PubMed: 41716339
- DOI: 10.1016/j.mtbio.2026.102902
- Low evidence
Protective effects of LL-SC-C2A2 were confirmed across cellular and animal models... This was achieved through ROS scavenging, pro-inflammatory cytokine reduction, intestinal barrier reinforcement, and restoration of gut microbiota homeostasis.
- Effect
- Beneficial
- Effect size
- Moderate