Lactococcus lactis MJC18 and Increased Dendritic Cell Activation

• Lactococcus lactis subsp. Cremoris C60 restores T Cell Population in Small Intestinal Lamina Propria in Aged Interleukin-18 Deficient Mice

  • 2020-10-27
  • Clinical Trial
  • Nutrients 12(11)
  • • Suguru Saito
    • N. Kakizaki
    • A. Okuno
    • T. Maekawa
    • N. Tsuji

  • PubMed: 33121026
  • DOI: 10.3390/nu12113287

  4 Insights on

  • Increased Dendritic Cell Activation

  • Low evidence
  • Animal Study

  The cytokines production and cellular activation markers expression were downregulated in the IL-18-deficient bone marrow derived dendritic cells (BMDCs) at the basal level, however, both activities were highly upregulated in HK-C60 stimulation as compared to those of WT cells.

  Effect

  Beneficial

  Effect size

  Moderate