Lactococcus lactis MJC18 and Reduced Intestinal Inflammation

• Protective effects of a novel probiotic strain, Lactococcus lactis ML2018, in colitis: in vivo and in vitro evidence.

  • 2019-06-14
  • Food & Function 10(2)
  • • Mei-ling Liu
    • Xiuxia Zhang
    • Y. Hao
    • Jinhua Ding
    • Jing Shen
    • Ziyu Xue
    • W. Qi
    • Zhongyuan Li
    • Yajian Song
    • Tongcun Zhang
    • Nan Wang

  • PubMed: 30724927
  • DOI: 10.1039/c8fo02301h

  2 Insights on

  • Reduced Intestinal Inflammation

  • Low evidence

  L. lactis ML2018 could inhibit DSS-induced intestinal inflammation by preventing the overproduction of proinflammatory factors, suppressing the infiltration of macrophages, controlling the fibrosis, improving the integrity of the intestinal epithelial barrier and upregulating the concentrations of short-chain fatty acids (SCFAs).

  Effect

  Beneficial

  Effect size

  Moderate