Lactococcus lactis MJC18 and Reduced Visceral Hypersensitivity

• Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract

  • 2022-06-21
  • Clinical Trial
  • eLife 11
  • • V. Laroute
    • C. Beaufrand
    • Pedro Gomes
    • S. Nouaille
    • V. Tondereau
    • M. Daveran-Mingot
    • V. Théodorou
    • H. Eutamene
    • M. Mercier-Bonin
    • M. Cocaign-Bousquet

  • PubMed: 35727704
  • DOI: 10.7554/eLife.77100

  1 Insight on

  • Reduced Visceral Hypersensitivity

  • Low evidence
  • Rigorous Journal
  • Animal Study

  L. lactis NCDO2118 significantly reduced visceral hypersensitivity induced by stress due to its glutamate decarboxylase (GAD) activity.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes