Probiotic Mixture Attenuates Colorectal Tumorigenesis in Murine AOM/DSS Model by Suppressing STAT3, Inducing Apoptotic p53 and Modulating Gut Microbiota.
- 2024-12-06
- Probiotics and antimicrobial proteins 17(4)
- Hoi Kit Matthew Leung
- Emily Kwun Kwan Lo
- Congjia Chen
- Fangfei Zhang
- Felicianna
- Marsena Jasiel Ismaiah
- Hani El-Nezami
- PubMed: 39641861
- DOI: 10.1007/s12602-024-10405-1
- Low evidence
- Rigorous Journal
- Animal Study
Prohep demonstrated exceptional anti-tumorigenesis effects in the AOM/DSS model... Prohep significantly reduced the total tumor count, total tumor size, caecum weight, colonic crypt depth, colonic inflammation, and collagen fibrosis.
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes