Lactococcus lactis VPro 34 and Reduced Tumor Volume

• Lactococci and lactobacilli as mucosal delivery vectors for therapeutic proteins and DNA vaccines

  • 2011-08-30
  • Microbial Cell Factories 10(S1)
  • • L. Bermúdez-Humarán
    • Pascale Kharrat
    • J. Chatel
    • P. Langella

  • PubMed: 21995317
  • DOI: 10.1186/1475-2859-10-S1-S4

  12 Insights on

  • Reduced Tumor Volume

  • Low evidence
  • Highly Cited

  Resulting recombinant lactococci strains have been tested successfully for their prophylactic and therapeutic effects in different animal models: i) against human papillomavirus type 16 (HPV-16)-induced tumors in mice.

  Effect

  Beneficial

  Effect size

  Large