Paecilomyces hepiali and Increased Immune System Activation

• Natural Deep Eutectic Solvent-Assisted Extraction, Structural Characterization, and Immunomodulatory Activity of Polysaccharides from Paecilomyces hepiali

  • 2022-11-18
  • Molecules 27(22)
  • • Yanbin Wang
    • Feijia Xu
    • Junwen Cheng
    • Xueqian Wu
    • Juan-hua Xu
    • Chunru Li
    • Wei-qi Li
    • Na Xie
    • Yuqin Wang
    • Liang He

  • PubMed: 36432126
  • DOI: 10.3390/molecules27228020

  1 Insight on

  • Increased Immune System Activation

  • Low evidence

  Immunomodulatory assays suggested that PHPS-D showed better performance than PHPS-W regarding pinocytic activity and the secretion of NO and pro-inflammatory cytokines (IL-6, TNF-α and IL-1β) by activating the corresponding mRNA expression in RAW264.7 cells.

  Effect

  Beneficial

  Effect size

  Moderate