Pediococcus acidilactici KABP-021 and Reduced Risk of Listeria Monocytogenes Infection

• In vivo study on the effectiveness of pediocin PA-1 and Pediococcus acidilactici UL5 at inhibiting Listeria monocytogenes.

  • 2009-08
  • Clinical Trial
  • International Journal of Food Microbiology 133(3)
  • • N. Dabour
    • Annina Zihler
    • E. Kheadr
    • C. Lacroix
    • I. Fliss

  • PubMed: 19541383
  • DOI: 10.1016/j.ijfoodmicro.2009.05.005

  2 Insights on

  • Reduced Risk of Listeria Monocytogenes Infection

  • Low evidence
  • Highly Cited
  • Animal Study

  Moreover, repeated doses (250 microg/day for three consecutive days) of purified pediocin PA-1 provided up to 2-log reductions in fecal listerial counts compared to the infected control group and slowed pathogen translocation into the liver and spleen, leading to the disappearance of L. monocytogenes infection in these two organs within six days.

  Effect

  Beneficial

  Effect size

  Large