Pediococcus acidilactici VPro29 and Maintained Higher Salivary Immunoglobulin A Levels

• A Double-Blind, Randomized, Placebo-Controlled Trial of Heat-Killed Pediococcus acidilactici K15 for Prevention of Respiratory Tract Infections among Preschool Children

  • 2020-07-03
  • RCT · n = 172
  • Nutrients 12(7)
  • • Haruka Hishiki
    • Tadaomi Kawashima
    • N. Tsuji
    • Naho Ikari
    • Ryo Takemura
    • H. Kido
    • N. Shimojo

  • PubMed: 32635408
  • DOI: 10.3390/nu12071989

  3 Insights on

  • Maintained Higher Salivary Immunoglobulin A Levels

  • High evidence

  The salivary sIgA level in the K15 group was maintained significantly higher than it was in the placebo group.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes