Pediococcus acidilactici and Reduced Colitis Severity

• Lactobacillus acidophilus combined with Pediococcus acidilactici ameliorates colitis.

  • 2026-03-04
  • Frontiers in microbiology 17
  • • Peilin Yu
    • Yuanming Jin
    • Da-Jeong Park
    • Mingzhu Wang
    • Chong-Su Cho
    • Chunri Yan
    • Fuliang Sun
    • Xin Jin
    • Keesun Yu
    • Young Jin Pyung
    • Cheol-Heui Yun
    • Lianhua Cui

  • PubMed: 41859447
  • DOI: 10.3389/fmicb.2026.1773197

  8 Insights on

  • Reduced Colitis Severity

  • Low evidence

  The results showed that the combined intervention was effective in reducing weight loss in mice with colitis and in mitigating the disease activity score. The combination significantly alleviated conditions such as colonic crypt dysfunction, goblet cell loss, and severe mucosal damage.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes