Pediococcus pentosaceus MAK99P15P and Reduced Clostridium difficile Infection

• Impact of encapsulating a probiotic (Pediococcus pentosaceus Li05) within gastro-responsive microgels on Clostridium difficile infections.

  • 2021
  • Clinical Trial
  • Food & Function 12(7)
  • • Jiaojiao Xie
    • Mingfei Yao
    • Yanmeng Lu
    • Mengjia Yu
    • Shengyi Han
    • D. Mcclements
    • Hang Xiao
    • Lanjuan Li

  • PubMed: 33734244
  • DOI: 10.1039/d0fo03235b

  5 Insights on

  • Reduced Clostridium difficile Infection

  • Low evidence
  • Animal Study
  • Clinical

  Encapsulated Li05 was better at inhibiting C. difficile infection than nonencapsulated Li05, as demonstrated through analysis of the probiotic survival rate, spleen weight, colonic histology, and inflammatory cytokine levels.

  Effect

  Beneficial

  Effect size

  Large