Propionibacterium freudenreichii MAK10P23F and Reduced Transepithelial Resistance

• Propionibacterium freudenreichii CIRM-BIA 129 mitigates colitis through S layer protein B-dependent epithelial strengthening.

  • 2024-02-01
  • Clinical Trial
  • American Journal of Physiology-Gastrointestinal and Liver Physiology 326(2)
  • • Marine Mantel
    • Tony Durand
    • A. Bessard
    • Ségolène Pernet
    • Julie Beaudeau
    • Juliana Guimaraes-Laguna
    • Marie-Bernadette Maillard
    • Éric Guédon
    • Michel Neunlist
    • Yves Le-Loir
    • Gwénaël Jan
    • M. Rolli-Derkinderen

  • PubMed: 37988603
  • DOI: 10.1152/ajpgi.00198.2023

  5 Insights on

  • Reduced Transepithelial Resistance

  • Low evidence
  • Animal Study

  It increased transepithelial electrical resistance (TEER) and inhibited permeability induced by inflammation, along with an increased ZO-1 expression.

  Effect

  Beneficial

  Effect size

  Moderate