Propionibacterium freudenreichii MAK10P23F and Reproduced Protective Effect via Extracellular Vesicles

• Propionibacterium freudenreichii CIRM-BIA 129 mitigates colitis through S layer protein B-dependent epithelial strengthening.

  • 2024-02-01
  • Clinical Trial
  • American Journal of Physiology-Gastrointestinal and Liver Physiology 326(2)
  • • Marine Mantel
    • Tony Durand
    • A. Bessard
    • Ségolène Pernet
    • Julie Beaudeau
    • Juliana Guimaraes-Laguna
    • Marie-Bernadette Maillard
    • Éric Guédon
    • Michel Neunlist
    • Yves Le-Loir
    • Gwénaël Jan
    • M. Rolli-Derkinderen

  • PubMed: 37988603
  • DOI: 10.1152/ajpgi.00198.2023

  5 Insights on

  • Reproduced Protective Effect via Extracellular Vesicles

  • Low evidence
  • Animal Study

  Extracellular vesicles (EVs) from P. freudenreichii CIRM-BIA129, carrying the surface layer protein (SlpB), reproduced the protective effect of P. freudenreichii CIRM-BIA129.

  Effect

  Beneficial

  Effect size

  Moderate