Rhizopus oryzae and Simultaneous 4-Vinyl Guaiacol Production

• Integrated omics-based analysis reveals the role of ferulic acid activating a co-production of 4-vinyl guaiacol and fumaric acid by Rhizopus oryzae.

  • 2026-04
  • Bioresource technology 445
  • • Xin Li
    • Shanshan Wu
    • Xueyu Tang

  • PubMed: 41638588
  • DOI: 10.1016/j.biortech.2026.134146

  2 Insights on

  • Simultaneous 4-Vinyl Guaiacol Production

  • Low evidence

  Co-supplementation of FA with glucose significantly enhanced metabolic performance, increasing fumaric acid yield by 16.9% and inducing simultaneous 4-VG synthesis.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes