Streptococcus salivarius K12 and Absence of Acute Toxicity

• Acute oral toxicity evaluation of synbiotic mixture containing Streptococcus salivarius K12 and Musa acuminata aqueous peel extract in Sprague-Dawley rats.

  • 2025-01
  • n = 5
  • Journal of Ayurveda and integrative medicine 16(1)
  • • Aalina Sakiinah Mohd Fuad
    • Mohd Hafiz Arzmi
    • Muhammad Ekmal Bakar
    • Izatus Shima Taib
    • Fazle Khuda
    • Nurrul Shaqinah Nasruddin

  • PubMed: 39681048
  • DOI: 10.1016/j.jaim.2024.101037

  1 Insight on

  • Absence of Acute Toxicity

  • Low evidence

  LD50 of the synbiotic formulation is higher than 2000 mg/kb, with no sign of acute toxicity observed on all parameters.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  No