Evaluation of safety and human tolerance of the oral probiotic Streptococcus salivarius K12: a randomized, placebo-controlled, double-blind study.
- 2011-09
- RCT · n = 53
- Food and Chemical Toxicology 49(9)
- Jeremy P. Burton
- S. Cowley
- R. Simon
- J. McKinney
- P. Wescombe
- J. Tagg
- PubMed: 21722694
- DOI: 10.1016/j.fct.2011.06.038
- High evidence
- Highly Cited
No statistically significant differences between the probiotic and placebo treated groups were detected in either the blood clinical chemistry or hematology results (P>0.05).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 1 × 10(10) cfu per day