Effect of probiotic lozenges on improvement in tympanometric classification within 12 weeks in children aged 3-6 years with adenoid hypertrophy and otitis media with effusion undergoing non-surgical management: a randomized controlled trial.
- 2026-02-09
- RCT
- Frontiers in cellular and infection microbiology 15
- Jun Shi
- Yu Liu
- Xiaoning Chen
- Xiaofei Hou
- He Chen
- Luomeng Chen
- Le Li
- PubMed: 41737842
- DOI: 10.3389/fcimb.2025.1736602
- High evidence
- Clinical
SSK12 produced significant group × time interactions for tympanometric parameters-positive changes in ΔTPP ... (all P<0.01)
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- ≥1×10^9 CFU/day