Impact of Streptococcus salivarius K12 on Nasopharyngeal and Saliva Microbiome: A Randomized Controlled Trial.
- 2020-12-08
- RCT · n = 121
- The Pediatric infectious disease journal 40(5)
- Suvi Sarlin
- Mysore V Tejesvi
- Jenni Turunen
- Petri Vänni
- Tytti Pokka
- Marjo Renko
- Terhi Tapiainen
- PubMed: 33298762
- DOI: 10.1097/inf.0000000000003016
- High evidence
- Large Human Trial
- Children
In children receiving K12 product, the mean abundance of S. salivarius was greater in saliva after the intervention (0.9% vs. 2.0%, P = 0.009).
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- oral K12 product for 1 month