Streptococcus salivarius K12 and Reduced Otopathogen Abundance

• Impact of Streptococcus salivarius K12 on Nasopharyngeal and Saliva Microbiome: A Randomized Controlled Trial.

  • 2020-12-08
  • RCT · n = 121
  • The Pediatric infectious disease journal 40(5)
  • • Suvi Sarlin
    • Mysore V Tejesvi
    • Jenni Turunen
    • Petri Vänni
    • Tytti Pokka
    • Marjo Renko
    • Terhi Tapiainen

  • PubMed: 33298762
  • DOI: 10.1097/inf.0000000000003016

  10 Insights on

  • Reduced Otopathogen Abundance

  • High evidence
  • Large Human Trial
  • Children

  At 1 month, the abundance of otopathogens in nasopharynx was lower in K12 group compared with that in control children (34% vs. 55%, P = 0.037).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  oral K12 product for 1 month