Streptococcus salivarius K12 and Reduced Pulmonary Inflammation

• Attenuated efficacy of Streptococcus salivarius K12 against Mycoplasma pneumoniae infection in mice.

  • 2026-03-13
  • RCT
  • BMC microbiology 26(1)
  • • Xiaoling Su
    • Yuan Li
    • Ying Huang
    • Haodang Luo
    • Chao Li
    • Xinchao Yi
    • Ning Wu
    • Jun He

  • PubMed: 41820920
  • DOI: 10.1186/s12866-026-04926-8

  1 Insight on

  • Reduced Pulmonary Inflammation

  • High evidence

  The Mp+K12 group showed a significant reduction in total white blood cell counts in BALF compared to the Mp + PBS group. Serum levels of TNF-α and IL-6 were notably lower in the Mp+K12 group than in the Mp + PBS group. TNF-α mRNA expression in lung tissue was also markedly reduced in the Mp+K12 group.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes