Streptococcus salivarius M18 and Improved Periodontal Clinical Parameters

• Adjunctive use of Streptococcus salivarius M18 probiotic in the treatment of periodontitis: a randomized controlled trial.

  • 2025-05-28
  • RCT · n = 55
  • 3 Biotech 15(6)
  • • Wei-Ju Chen
    • Lavanya Ajay Sharma
    • Peng Shao
    • Tia Griffith
    • Robert Love
    • Rohit Jain
    • John Hale
    • Ajay Sharma

  • PubMed: 40443548
  • DOI: 10.1007/s13205-025-04363-w

  3 Insights on

  • Improved Periodontal Clinical Parameters

  • High evidence

  The test group demonstrated significantly improved PPD, BoP, and PI compared to the placebo group at post-treatment follow-ups, although no significant difference was observed in CAL.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes