Effect of probiotic colonization on oral hygiene and ventilator-associated pneumonia in ICU patients: a triple-blind randomized controlled trial.
- 2026-02-03
- RCT
- BMC infectious diseases 26(1)
- Ahmad Salehi
- Farzad Ebrahimzadeh
- Ali Behzadfar
- Maryam Hashemi
- Sajad Yarahmadi
- PubMed: 41634618
- DOI: 10.1186/s12879-026-12711-1
- High evidence
- Clinical
the clinical pulmonary infection score decreased in the intervention group but increased in the control group (−0.67 ± 1.29 vs. +1.35 ± 1.58; adjusted F = 30.27, p < 0.001).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- two daily doses of 250 mg of Streptococcus salivarius probiotic solution